OTC is short for over-the-counter drugs. The FDA defines OTC drugs as safe and effective for use by the general public without a doctor’s prescription.

The following are examples of active ingredients in common over-the-counter drugs: acetaminophen (Tylenol), ibuprofen (Advil or Motrin), simethicone (Mylicon gas drops), colloidal oatmeal (Aveeno Body Wash and Lotion), and zinc oxide (Desitin or Boudreaux’s Butt Paste).